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Endocrinology, Vol 98, 1430-1433, Copyright © 1976 by Endocrine Society


ARTICLES

Oxytocin content of microdissected areas of rat hypothalamus

JM George, S Staples and BM Marks

Oxytocin content has been measured by radioimmunoassay in microdissected hypothalamic nuclei. Equal concentrations of oxytocin were found in the supraoptic and the paraventricular nuclei, indicating that both are major sources of the hormone. The concentration of oxytocin in the median eminence was more than three times that in either the supraoptic or the paraventricular nuclei, and significant amounts of oxytocin were also found in the arcuate nucleus and in tow anterior hypothalamic nuclei.


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J. George
Immunoreactive vasopressin and oxytocin: concentration in individual human hypothalamic nuclei
Science, April 21, 1978; 200(4339): 342 - 343.
[Abstract] [PDF]




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