help button home button Endocrine Society Endocrinology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology, doi:10.1210/en.2004-1281
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
146/5/2176    most recent
Author Manuscript (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cifuentes, M.
Right arrow Articles by Rojas, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cifuentes, M.
Right arrow Articles by Rojas, C.
Endocrinology Vol. 146, No. 5 2176-2179
Copyright © 2005 by The Endocrine Society

BRIEF COMMUNICATION

Calcium-Sensing Receptor Expression in Human Adipocytes

Mariana Cifuentes, Cecilia Albala and Cecilia Rojas

Institute of Nutrition and Food Technology, University of Chile, Casilla 138-11, Santiago, Chile

Address all correspondence and requests for reprints to: Mariana Cifuentes, Institute of Nutrition and Food Technology-Universidad de Chile, El Líbano 5524, Macul, Casilla 138-11, Santiago, Chile. E-mail: mcifuentes{at}inta.cl.

The presence of the extracellular calcium-sensing receptor (CaSR) has been demonstrated in numerous cells that are key in the control of serum calcium concentrations, underscoring its relevance in systemic calcium homeostasis. The more recent evidence of its presence in tissues not involved in this function has broadened the spectrum of interest in this protein, now known to regulate diverse cell functions such as proliferation, differentiation, and apoptosis. This study shows the expression of CaSR in human omental adipose tissue, isolated adipocytes, and adipocyte progenitor cells as assessed by RT-PCR and immunoblotting. This is the first report of CaSR being expressed in human adipocytes and adipocyte progenitor cells, opening the possibility to investigate the physiological implications and thus contributing a novel component for adipose tissue biology research.




This article has been cited by other articles:


Home page
 Am. J. Physiol. Renal Physiol.Home page
G. Molostvov, S. James, S. Fletcher, J. Bennett, H. Lehnert, R. Bland, and D. Zehnder
Extracellular calcium-sensing receptor is functionally expressed in human artery
Am J Physiol Renal Physiol, September 1, 2007; 293(3): F946 - F955.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 2005 by The Endocrine Society