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Endocrinology, Vol 113, 814-815, Copyright © 1983 by Endocrine Society

ARTICLES

N-alpha-formyl-tyrosyl-relaxin - a reliable tracer for relaxin radioimmunoassay

C Schwabe

Porcine relaxin has no radio-iodinatable amino acid and must therefore be modified prior to iodination. In this paper a synthesis of an iodinatable relaxin derivative is described which leads to a fairly uniform product. The nature of the modifying group (formyltyrosine) allows for easy and accurate estimation of the degree of substitution attained as well as determination of the position where substitution has occurred.




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Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1983 by The Endocrine Society