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Endocrinology, Vol 100, 1391-1393, Copyright © 1977 by Endocrine Society

ARTICLES

Thyrotropin-releasing hormone in rat brain: nyctohemeral variations

R Collu, PD Ruisseau, Y Tache and JR Ducharme

The concentration of thyrotropin-releasing hormone (TRH) was measured by specific radioimmunoassay in three different brain regions of rats sacrificed every 4 h over a 24 h period. TRH concentration reached a zenith at 1200 h both in the hypothalamus and the amygdala but did not vary in the forebrain. These results indicate that a nyctohemaral variation of TRH levels exists in hypothalamic and extrahypothalamic brain areas.


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A. Kalsbeek, E. Fliers, A. N. Franke, J. Wortel, and R. M. Buijs
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[Abstract] [Full Text] [PDF]


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